Season 1 is the first season of Artemis & Friends. It will appear on YouTube in the near future.
- The Queen of Make-Believe
- My Family's Just Right for Me
- Playing it Safe
- Hop to It!
- Eat, Drink and Be Healthy!
- Four Seasons Day
- The Treasure of Rainbow Beard
- Going Places!
- Caring Means Sharing
- Down on Artemis' Farm
- What's That Shadow?
- Happy Birthday, Artemis!
- Alphabet Soup!
- Our Earth, Our Home
- Let's Help Ariel!
- Be a Friend
- I Just Love Bugs
- When I Grow Up...
- 1-2-3-4-5 Senses!
- Practice Makes Music
- Hi, Neighbor!
- A Camping We Will Go!
- A Splash Party, Please
- Carnival of Numbers
- A World of Music
- Doctor Artemis is Here!
- Oh, What a Day!
- Home Sweet Homes
- Hola, Mexico!
- Everyone is Special
- Barney - Artemis (Sailor Moon)
- Baby Bop - Luna (Sailor Moon)
- Michael - Max (Dragon Tales)
- Derek - George Shrinks
- Tina - Lilo (Lilo & Stitch)
- Luci - Nani (Lilo & Stitch)
- Min - Lita/Sailor Jupiter (Sailor Moon)
- Shawn - Alvin Seville (Alvin and the Chipmunks)
- Kathy - Diana (Anne of Green Gables: The Animated Series)
- Tosha - May (Pokemon)
- Genie as James Turner ("Eat, Drink and Be Healthy!")
- Scallywag as Rainbow Beard the Pirate ("The Treasure of Rainbow Beard")
- Peter Griffin as Farmer Henderson ("Down on Artemis' Farm")
- Ariel as Mother Goose ("Let's Help Ariel!")
- Velma Dinkley as Patty ("1-2-3-4-5 Senses!")
- Human Naveen as Greg Murray ("Practice Makes Music")
- King Fergus as Fergus McClaren ("A World of Music")
- Flannery as Lesley Chudnow ("A World of Music")
- Human Tiana as Efei Almani ("A World of Music")
- Mulan as Gloria Chen ("A World of Music")
- Tulio as Abundio Ortiz ("A World of Music")
- Chel as Rebecca Garcia ("Hola, Mexico!")
- Winston as Mr. Delivery Man ("Everyone Is Special")
- This season is Nani's only regular appearance. She would appear later as a guest in The Exercise Circus!.
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