Cast
- Osmosis Jones - Buster Baxter (Arthur)
- Drix - Arthur Read
- Leah Estrogen - Bunnie Rabbot (Sonic the Hedgehog (SatAM))
- Police Chief - Archibald the Koala
- Mayor Phlegmming - Jake (Kipper)
- Tom Colonic - Monterey Jack (Chip n Dale Rescue Rangers)
- Thrax - Spydra (Gadget Boy)
- Bruiser - Dawn/The Princess (Danger Mouse)
- Spider Legs - Dr. Loo-Cifer (Danger Mouse)
- The Crime Boss - Oil Can Harry (Mighty Mouse)
- The Flu Germ - Boris (Gadget Boy)
- Frank Detorre - Uncle Grizzly (Grizzly Tales for Gruesome Kids)
- Shane Detorre - Bubbles (The Powerpuff Girls)
- Mrs. Boyd - Mrs. Wicket (Mr. Bean)
- Uncle Bob - Mr. Bean
- Chill - ???