A spoof of the 2017 computer-animated comedy film Captain Underpants: The First Epic Movie.
- George Beard - Milhouse Van Houten (The Simpsons)
- Harold Hutchins - Bart Simpson (The Simpsons)
- Professor Poopypants - Tom Cat (Tom and Jerry)
- Benjamin "Benny" Krupp/Captain Underpants - Garfield (Garfield)
- Melvin Sneedly - Stewie Griffin (Family Guy)
- Edith - Arlene (Garfield)
- Ms. Tara Ribble - Scarlet Overkill (Minions)
- Mr. Rected - Pete (Mickey Mouse)
- Mr. Morty Fyde - Jimbo (The Boss Baby)
- Edith Anthrope - Taffyta Muttonfudge (Wreck-It Ralph)
- Mr. Meaner - Lots-O'-Huggin-Bear (Toy Story)
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