Computress is a living computer who only appeared in the episode Dexter and Computress Get Mandark!. He is Mandark's "brother". The character was created by six and half year-old Tyler Samuel Lee who won a special contest on Cartoon Network to write an episode of Dexter's Laboratory.
- In Kit's Laboratory he is played by Boo Boo Bear.
- In Tori's Laboratory he is played by Donha.
- In Ron's Laboratory he is played by Wade Load.