Daria the Vampire Slayer is a parody of Buffy the Vampire Slayer.
- Daria Morgendorffer (Daria) as Buffy Summers
- Bonnie Rockwaller (Kim Possible) as Cordelia Chase
- Hermione Granger (Harry Potter) as Willow Rosenberg
- Professor Utonium (The Powerpuff Girls) as Rupert Giles
- Marshall Lee (Adventure Time) as Spike
- Beast Boy (Teen Titans) as Xander Harris
- Lars (Steven Universe) as Oz
- Elsa (Frozen) as Anya Jenkins
- Robin (Teen Titans) as Angel
- Quinn Morgendorffer (Daria) as Dawn Summers
- Raven (Teen Titans) as Tara MaClay
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