The eastern wolf (Canis lycaon), also known as the eastern timber wolf, Algonquin wolf or deer wolf, is a canid native to the northeastern side of North America's Great Lakes region. It is a medium-sized canid which, like the red wolf, is intermediate in size between the coyote and Northwestern wolf. It primarily preys on white-tailed deer, but may occasionally attack moose and beaver.
- It played Professor Utonium in The Powerpuff Wolves, The Powerpuff Wolves Movie, The Powerpuff Wolves (2016), The Powerpuff Canids, The Powerpuff Canids Movie, The Powerpuff Canids (2016)
- They played Wolves in We Bare Cervids
- It played Miss Keane in The Powerpuff Foxes, The Powerpuff Foxes Movie, and The Powerpuff Foxes (2016)
- It played Fuzzy Lumpkins in The Powerpuff American Animals and The Powerpuff American Animals Movie
- It played Ace in The Powerpuff Badgers and The Powerpuff Badgers Movie
- It played Emma (Mermaid) in Mako Wolves (NatureRules1 and GavenLovesAnimals Style)