Cast[]
- Thomas, Edward, Henry, Gordon, James, Percy and Toby as Sulley
- Ami and Yumi (from Hi Hi Puffy AmiYumi/Thomas & Friends/Rodney, Fender, Shaggy and Scooby-Doo of Robots Tunes Get A Clue/Penguins of Madagascar) as Mike
- Rosie as Boo
- Emily as Celia Mae
- Murdoch as Yeti
- Gru (from Despicable Me) as George
- Bill as Needleman
- Ben as Smitty
- Diesel as Randall
- Spencer as Mr. Waternoose
- Daisy as Roz
- Megamind (from Despicable Me/Megamind) as Charlie
- Duck as Jerry
- Molly as Betty
- Derek as Bile
- Fergus as Fungus
- Harvey as Waxford
- Molly as Ms. Flint
- Skarloey, Rheneas, and Sir Handel as Flint's Assistants
- Lightning McQueen (from Cars/Thomas and Friends BWBA) as Tony
- Mater (from Cars/Thomas & Friends BWBA) as Spike Jones
- Neville as Pete "Claws" Ward
- Stepney as Claws Ward's Assistant
- Rodney Copperbottom (from Robots Tunes/Hi Hi Puffy AmiYumi/Thomas & Friends) as Ted
- Oliver as Lankey Schmidt
- Whiff as News Reporter #1
- Stanley as News Reporter #2
- Hiro as Sushi Chef
- Billy as Baby Smitty