Arthur Read (sometimes), Muffy Crosswire (sometimes), Brain Powers (sometimes)
Red, sports (especially soccer, football, kickball, bowling, and baseball), horses, spending time with her friends, being the animals (especially a hippo), being sexy, her butt, dancing, boys (specially Arthur and the Brain)
Cherry soda, getting into trouble, Muffy's antics, being embarrassed, rejection, being insulted, bad luck
Even though Francine doesn't like having her hair done like her best friend Muffy does, she has had a few alternate hairstyles in the series. Her signature hairstyle is a straight flip, even though it's not flat. In Arthur's Valentine, she has wavy hair when she becomes Arthur's secret admirer while at a cinema sitting in seat 3B. In "Francine's Bad Hair Day", Muffy urges her to get her hair done for school pictures, and Francine first wants the Prom Queen hairstyle that Muffy was getting. Francine has a dream where she's playing kickball and has super-long hair that can be used to retrieve the ball or reach a base. When Francine checks out the results, she is given a tightly curled hairstyle instead. After "Francine's Bad Hair Day", she has since kept her signature hairstyle. In the end of "The Lousy Week", she and Muffy are both given a buzz cut to eliminate lice from reproducing in their hairs.