The Uranimated18 spoof for "Osmosis Jones".
- Osmosis Jones - Mike (Total Drama)
- Drix - Wreck-It Ralph
- Frank - Homer Simpson (The Simpsons)
- Leah Estrogen - Zoey (Total Drama)
- Police Chief - Comander Nebula (Buzz Lighyear of Star Command)
- Mayor Phleming - Mr. O'Hare (The Lorax)
- Thrax - Hades (Hercules)
- Shane - Lisa Simpson (The Simpsons)
- Bruiser - Oogie Boogie (The Nightmare Before Christmas)
- Tom Culonic - Megamind
- Spider Legs - Randall Boggs (Monsters Inc.)
- Crime Boss - Henry J. Waternoose (Monsters Inc.)
- Flu Germ - J. Worthington Foulfellow (Pinocchio)
- Of course, in this spoof, you'll be hearing Homer saying "D'oh!"; "Hee, hee, hee, hee"; "Why, you little!" (when fighting a zoo monkey for his egg at lunchtime) and sobbing emotionally when singing "Alone Again (Naturally)" in his car.
- Lisa's mother Marge is absent in this spoof but she is mentioned as Shane's mother passed away at least two years before the movie begins
- Lisa recalls to her father about packing her a turkey Slim Jim sandwich for lunch, despite that she is a vegetarian
- Homer mentions that Lisa was fed cheeseburgers as a baby, long before she became a vegetarian
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