Disney and Sega's tv-spoof of 1998-2005 tv series of "The Powerpuff Girls".
- Blossom - Betty Barrett (Atomic Betty)
- Bubbles - Zelda (The Legend of Zelda)
- Buttercup - Paloma (Atomic Betty)
- Professor Utonium - Dallben (The Black Cauldron)
- The Mayor - Senator Masterson (Inhumanoids)
- Miss Keane - Cinderella (both voiced by Jennifer Hale)
- Miss Bellum - Sandra Shore (Inhumanoids)
- Brick - Noah Parker (Atomic Betty)
- Boomer - Link (The Legend of Zelda)
- Butch - Chaz Lang (Atomic Betty)
- Mojo Jojo - Vincent Cadby (Ace Ventura: When Nature Calls)
- Giant Mojo Jojo - Numbertaker (Numberjacks)
- Him - Judge Doom (Who Framed Roger Rabbit)
- Ima Goodlady - Princess Aurora (Sleeping Beauty)
- Sedusa - Lois Einhorn/Ray Finkle (Ace Ventura: Pet Detective)
- Teenage Blossom - Sam (Totally Spies!)
- Teenage Bubbles - Alex (Totally Spies!)
- Teenage Buttercup - Clover (Totally Spies!)
- Teenage Brick - Josh (Team Galaxy)
- Teenage Boomer - Principal Kirkpatrick (Team Galaxy)
- Teenage Butch - Java the Caveman (Martin Mystery)
- Betty Barrett and Blossom have same voice.
- Both Cinderella and Miss Keane were voiced by Jennifer Hale.